Cardiovascular Development: Volume 18 (Advances in Developmental Biology #18) (Hardcover)

Cardiovascular Development: Volume 18 (Advances in Developmental Biology #18) By Paul Wassarman (Editor), Rolf Bodmer (Volume Editor) Cover Image

Cardiovascular Development: Volume 18 (Advances in Developmental Biology #18) (Hardcover)

By Paul Wassarman (Editor), Rolf Bodmer (Volume Editor)
In 1993, Rolf Bodmer described a gene he named tinman that was required for the formation of the dorsal aorta of the fly. Flies without a functional tinman gene had no heart. Quickly, mammalian counterparts of the tinman gene were identified and found to be expressed by early cardiomyogenic precursors and by cardiomyocytes throughout heart development. Since then, significant progress has been made in the understanding of molecular and genetic determinants of heart formation. An ever growing number of genes have been identified that are required for cardiogenesis, as evidenced by severe abnormalities in cardiac development produced by inactivation in the mouse or inhibition of gene function in other model organisms. Cardiovascular Development covers some of the latest research in the study of heart formation. Volume Editor Rolf Bodmer has assembled a world-class list of contributors whose research uses a variety of animal models and whose findings are certain to enhance our understanding of this exciting field.
Product Details ISBN: 9780444530141
ISBN-10: 0444530142
Publisher: Elsevier Science
Publication Date: November 13th, 2007
Pages: 454
Language: English
Series: Advances in Developmental Biology