Regulatory Rnas: Basics, Methods and Applications (Paperback)

Regulatory Rnas: Basics, Methods and Applications By Bibekanand Mallick (Editor), Zhumur Ghosh (Editor) Cover Image

Regulatory Rnas: Basics, Methods and Applications (Paperback)

By Bibekanand Mallick (Editor), Zhumur Ghosh (Editor)


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Renaissance of Regulatory RNAs.- Diversity, overlap and relationships in the small RNA landscape.- Fragments of small nucleolar RNAs as a new source for non-coding RNAs.- Small regulatory RNAs (sRNAs) - key players in prokaryotic metabolism, stress response and virulence.- The canonical RNA interference pathway in animals.- Generation of functional long non-coding RNA through transcription and natural selection.- MicroRNA regulation of neuronal differentiation and plasticity.- Long Non-coding RNA Function and Expression in Cancer.- Expression profiling of ncRNAs employing RNP libraries and custom LNA/DNA microarray analysis.- Targeted methods to improve small RNA profiles generated by deep sequencing.- Biocomputational identification of bacterial small RNAs and their target binding sites.- Identifying functional miRNA targets using over-expression and knockdown methods.- Identification of lncRNAs using computational and experimental approaches.- Experimental analyses of RNA-based regulations in Bacteria.- Microregulators ruling over pluripotent stem cells.- The role of RNA-interference in targeting the cancer stem cell and clinical trials for cancer.- microRNAs in development, stem cell differentiation and regenerative medicine.- The role of microRNAs in neurodegenerative diseases: Implications for early detection and treatment.- siRNA therapeutic design: tools and challenges.- Artificial MicroRNA and its Applications.- Deep sequencing of microRNAs in cancer: Expression profiling and its applications.

Product Details ISBN: 9783642442841
ISBN-10: 3642442846
Publisher: Springer
Publication Date: April 13th, 2014
Pages: 554
Language: English